Zhang, Tianyu; Yang, Zhenkun; Zhou, Dapeng; Meng, Fuliang; Han, Zhengyu; Huang, Hai published the artcile< Non-metal Lewis acid-catalyzed cross-Claisen condensation for β-keto esters>, Safety of Ethyl 2-(3-bromophenyl)acetate, the main research area is alkoxy silyl ketene acetal keto ester Lewis acid catalyst; keto alkoxy ester cehmoselective preparation Claisen condensation.
A new catalytic and highly chemoselective cross-Claisen condensation of esters was disclosed. In the presence of TBSNTf2 as a non-metal Lewis acid, various esters can undergo cross-Claisen condensation to form β-keto esters which are important building blocks. Compared with the traditional Claisen condensation, this process, employing silyl ketene acetals (SKAs) as carbonic nucleophiles to achieve cross-Claisen condensation, requires mild conditions and has good tolerance of functional groups.
Organic & Biomolecular Chemistry published new progress about 1,3-Dicarbonyl compounds Role: SPN (Synthetic Preparation), PREP (Preparation). 14062-30-7 belongs to class bromides-buliding-blocks, and the molecular formula is C10H11BrO2, Safety of Ethyl 2-(3-bromophenyl)acetate.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary