Zhang, Lei; Hu, Xile published the artcile< Nickel catalysis enables convergent paired electrolysis for direct arylation of benzylic C-H bonds>, Formula: C7H4BrF3, the main research area is toluene aryl bromide nickel catayst electrochem arylation; arylmethylbenzene preparation.
Convergent paired electrosynthesis is an energy-efficient approach in organic synthesis; however, it is limited by the difficulty to match the innate redox properties of reaction partners. Here we use nickel catalysis to cross-couple the two intermediates generated at the two opposite electrodes of an electrochem. cell, achieving direct arylation of benzylic C-H bonds. This method yields a diverse set of diarylmethanes, which are important structural motifs in medicinal and materials chem. Preliminary mechanistic study suggests oxidation of a benzylic C-H bond, Ni-catalyzed C-C coupling, and reduction of a Ni intermediate as key elements of the catalytic cycle.
Chemical Science published new progress about Alkylarenes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 401-78-5 belongs to class bromides-buliding-blocks, and the molecular formula is C7H4BrF3, Formula: C7H4BrF3.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary