In 2022,Yu, Shaoze; Shen, Guosong; He, Faqian; Yang, Xiaoyu published an article in Chemical Communications (Cambridge, United Kingdom). The title of the article was 《Asymmetric synthesis of planar-chiral macrocycles via organocatalyzed enantioselective macrocyclization》.Application of 17696-11-6 The author mentioned the following in the article:
A novel enantioselective macrocyclization method was developed for the asym. synthesis of planar-chiral macrocycles I [R1 = Br, C≡Ccyclopropyl, C≡CPh, etc.; R2 = Me, Et; R3 = Piv, C(O)CMe2Et; n = 0, 1, 2, 3, 4] through chiral phosphoric acid-catalyzed intramol. addition of the hydroxy group with the allenamide moiety. A series of planar-chiral macrocycles bearing various ring sizes (18-member to 22-member) and various functional groups were generated with good to high enantioselectivities. In the part of experimental materials, we found many familiar compounds, such as 8-Bromooctanoic acid(cas: 17696-11-6Application of 17696-11-6)
8-Bromooctanoic acid(cas: 17696-11-6) acid is used in the synthesis of 8-(N-Methyl-4,4′-bipyridinyl)- octanoic acid. 8-Mercaptooctanoic acid was prepared from 8-bromooctanoic acid.Application of 17696-11-6
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary