《Human serum albumin as an intrinsic signal amplification amplifier for ultrasensitive assays of the prostate-specific antigen in human plasma》 was published in Chemical Communications (Cambridge, United Kingdom) in 2020. These research results belong to Yang, Le; Zheng, Jing; Zou, Zhen; Cai, Haiyan; Qi, Peng; Qing, Zhihe; Yan, Qi; Qiu, Liping; Tan, Weihong; Yang, Ronghua. Product Details of 2969-81-5 The article mentions the following:
As the most abundant protein in blood, human serum albumin (HSA) is usually regarded as an interferent in clin. mol. diagnosis. Herein, the authors report that HSA is an endogenous signal amplifier for the detection of the prostate-specific antigen (PSA) in human plasma. This is the first study to use intrinsic biol. components as the signal amplifier in blood tests. The experimental process involved the reaction of Ethyl 4-bromobutyrate(cas: 2969-81-5Product Details of 2969-81-5)
Ethyl 4-bromobutyrate(cas: 2969-81-5) belongs to bromides. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon–bromine bond is electrophilic, i.e. alkyl bromides are alkylating agents.Product Details of 2969-81-5
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary