《Defluorinative Functionalization of Pd(II) Fluoroalkyl Complexes》 was published in Journal of the American Chemical Society in 2020. These research results belong to Wade Wolfe, Michael M.; Shanahan, James P.; Kampf, Jeff W.; Szymczak, Nathaniel K.. Synthetic Route of C9H11BrO3 The article mentions the following:
When subjected to arylboranes, anionic trifluoromethyl and difluorobenzyl palladium(II) complexes undergo fluoride abstraction followed by 1,1-migratory insertion. The resulting intermediate fluoroalkyl species can be induced to undergo a subsequent transmetalation and reductive elimination from either an in situ formed fluoroboronate (FB(Ar3)-) or an exogenous boronic acid/ester (ArB(OR)2) and nucleophilic activator, representing a net defluorinative arylation reaction. The latter method enabled a structurally diverse substrate scope to be prepared from either an isolated palladium-CF3 complex, or from Pd(PPh3)4 and other com. available reagents. In the experiment, the researchers used many compounds, for example, 1-Bromo-3,4,5-trimethoxybenzene(cas: 2675-79-8Synthetic Route of C9H11BrO3)
1-Bromo-3,4,5-trimethoxybenzene(cas: 2675-79-8) is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.Synthetic Route of C9H11BrO31-Bromo-3,4,5-trimethoxybenzene can be used to synthesize N,N′-diarylated indolo[3,2-b]carbazole derivatives, which can find applications in electrophotography.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary