《Two color photoflow chemistry for macromolecular design》 was written by Van De Walle, Matthias; De Bruycker, Kevin; Blinco, James P.; Barner-Kowollik, Christopher. Safety of Ethyl 4-bromobutyrate And the article was included in Angewandte Chemie, International Edition in 2020. The article conveys some information:
We report a photochem. flow setup that exploits λ-orthogonal reactions using two different colors of light (λ1=350 nm and λ2=410 nm) in sequential online irradiation steps. Critically, both photochem. reactive units (a visible-light reactive chalcone and a UV-activated photo-caged diene) are present in the reaction mixture We demonstrate the power of two color photoflow by the wavelength-selective end group modification of photo-caged polymer end groups and the subsequent polymer ring closure driven by a [2+2] cycloaddition Importantly, we evidence that the high energy gate does not induce the visible light reaction of the chalcone, which attests the true λ-orthogonal nature of the flow reaction system. For the first time, this study opens the realm of photoflow reactions to λ-orthogonal photochem. In the part of experimental materials, we found many familiar compounds, such as Ethyl 4-bromobutyrate(cas: 2969-81-5Safety of Ethyl 4-bromobutyrate)
Ethyl 4-bromobutyrate(cas: 2969-81-5) belongs to bromides. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact.Safety of Ethyl 4-bromobutyrate
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary