Mitchell, T. Andrew; Bode, Jeffrey W. published their research in Journal of the American Chemical Society on December 23 ,2009. The article was titled 《Synthesis of Dialkyl Ethers from Organotrifluoroborates and Acetals》.Formula: C6H4BBrF3K The article contains the following contents:
The formation of ethers by C-O bond formation under harsh basic or acidic conditions is an entrenched synthetic disconnection in organic chem. We report a strategic alternative that involves the BF3·OEt2-promoted coupling of stable, easily prepared acetals with widely available potassium aryl-, alkenyl-, and alkynyltrifluoroborates. This fast, operationally simple process offers straightforward access to dialkyl ethers, many of which would be difficult to prepare using classical methods. The use of MOM-protected alcs. and acetal-protected aldehydes enables ether formation without recourse to protecting-group manipulations or strong bases. In addition to this study using potassium (3-bromophenyl)trifluoroborate, there are many other studies that have used potassium (3-bromophenyl)trifluoroborate(cas: 374564-34-8Formula: C6H4BBrF3K) was used in this study.
potassium (3-bromophenyl)trifluoroborate(cas: 374564-34-8) belongs to organobromine compounds.Most of the natural organobromine compounds are produced by marine organisms , and several brominated metabolites with antibacterial , antitumor , antiviral , and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. Formula: C6H4BBrF3K
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary