Menzel, Karsten; Dimichele, Lisa; Mills, Paul; Frantz, Doug E.; Nelson, Todd D.; Kress, Michael H. published the artcile< Regioselective halogen-metal exchange reaction of 3-substituted 1,2-dibromo arenes: the synthesis of 2-substituted 5-bromobenzoic acids>, Formula: C8H3BrO3, the main research area is substituted dibromoarene isopropylmagnesium chloride regioselective halogen metal exchange; bromoarene substituted preparation; bromobenzoic acid substituted preparation; regioselective halogen metal exchange reagent isopropylmagnesium chloride.
Regioselective halogen-metal exchange reactions using isopropylmagnesium chloride were carried out on 3-substituted 1,2-dibromo arenes, e.g., I. When the 3-substituent was either electron-withdrawing and/or possessed lone pair electrons that enabled chelation of isopropylmagnesium chloride, a high regioselectivity for the halogen-metal exchange adjacent to the 3-substituents resulted.
Synlett published new progress about Aromatic carboxylic acids Role: SPN (Synthetic Preparation), PREP (Preparation) (bromo-). 82-73-5 belongs to class bromides-buliding-blocks, and the molecular formula is C8H3BrO3, Formula: C8H3BrO3.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary