Liang, Zhi-Qin; Gao, Zhong-Hua; Jia, Wen-Qiang; Ye, Song published the artcile< Bifunctional N-Heterocyclic Carbene Catalyzed [3+4] Annulation of Enals and Aurones>, HPLC of Formula: 3893-18-3, the main research area is benzofuran lactone fused preparation diastereoselective enantioselective; aurone enal annulation bifunctional heterocyclic carbene catalyst; N-heterocyclic carbenes; annulation; kinetic control; lactones; organocatalysis.
Bifunctional N-heterocyclic carbenes with a free hydroxy group were demonstrated as efficient catalysts for the [3+4] annulation of enals RHC:CHCHO (R = 4-H3CCO6H4, 2-ClC6H4, furan-2-yl, CH2CH2CH3, etc.) with aurones I [Ar = C6H5, naphthalen-1-yl, furan-2-yl, styryl, etc.] to give the corresponding benzofuran-fused ε-lactones II in good yields with good diastereoselectivities and excellent enantioselectivities. The control experiments reveals that the [3+4] cycloadducts are kinetically favored and could be transformed to the thermodynamically favored [3+2] cycloadducts with a non-bifunctional NHC catalyst.
Chemistry – A European Journal published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, HPLC of Formula: 3893-18-3.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary