Safety of Benzyl 2-bromoacetateIn 2022 ,《Photocatalytic 1,2-oxo-alkylation reaction of styrenes with diazoacetates》 was published in Chemical Communications (Cambridge, United Kingdom). The article was written by Li, Fang; Zhu, Siqi; Koenigs, Rene M.. The article contains the following contents:
The photocatalytic 1,2-difunctionalization reaction of styrenes with acceptor-only diazoalkanes are reported. In the presence of DABCO and tBuOOH, the carbene reactivity of diazoalkanes can be suppressed and a 1,2 oxo-alkylation reaction can be achieved (32 examples, up to 94% yield) without the formation of cyclopropane byproducts via the formation of radical intermediates from Et diazoacetate. In the experiment, the researchers used many compounds, for example, Benzyl 2-bromoacetate(cas: 5437-45-6Safety of Benzyl 2-bromoacetate)
Benzyl 2-bromoacetate(cas: 5437-45-6) has been used in the alkylation of (-)-2,3-O-isopropylidene-D-threitol that afforded lipopeptide, 2-[(4R,5R)-5-({[(9H-fluoren-9-yl)methoxy]carbonylaminomethyl}-2,2-dimethyl-1,3-dioxolan-4-yl)methoxy]acetic acid.Safety of Benzyl 2-bromoacetate
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary