Hu, Yuanyuan; Luo, Honggen; Tu, Xiangtu; Xue, Han; Jin, Hongwei; Liu, Yunkui; Zhou, Bingwei published their research in Chemical Communications (Cambridge, United Kingdom) in 2021. The article was titled 《Selective cine-arylation of tert-cyclobutanols with indoles enabled by nickel catalysis》.Name: 5-Bromobenzo[d][1,3]dioxole The article contains the following contents:
In previous literature, tert-cyclobutanols are widely studied for C-C bond activation exclusively leading to the formation of ordinary γ-substituted ketones. Herein, authors report on nickel-catalyzed cine-arylation of tert-cyclobutanols with indoles to access β-aryl ketones with an unusual site-selectivity at the C3-position of tert-cyclobutanols. The reaction features earth-abundant nickel catalysis, excellent regioselectivity, high atom-economy, and broad substrate scope. The experimental part of the paper was very detailed, including the reaction process of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4Name: 5-Bromobenzo[d][1,3]dioxole)
Furthermore, the coupling of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4) with β-methallyl alcohol was catalyzed by Pd(OAc)2 in combination with P(t-Bu)3.Name: 5-Bromobenzo[d][1,3]dioxole
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary