Hazra, Gurupada; Mishra, Gitanjali; Dandela, Rambabu; Thirupathi, Barla published the artcile< A Method to Access Highly Functionalized Dibenzobicyclo[3.2.1]octadienones: Application to the Construction of the 6/6/5/6/6 Carbon Skeleton of Rubialatin A>, Recommanded Product: 2-Bromo-3-methoxyphenol, the main research area is keto indandione aryne insertion diastereoselective; dibenzobicyclo octadienone stereoselective preparation.
The dibenzobicyclo[3.2.1]octadienone scaffold, which has been found in naphthocyclinones, engelharquinones, rubialatin A, etc., has been synthesized under mild transition metal-free conditions by aryne insertion reaction with 2-keto-1,3-indandiones. The application of this methodol. has been demonstrated for the synthesis of the 6/6/5/6/6 scaffold of rubialatin A. 1H NMR exptl. studies confirm that the reaction proceeds through the formation of benzocyclobutane followed by a 7-member carbocycle ring.
Journal of Organic Chemistry published new progress about Alkynes, arynes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 135999-16-5 belongs to class bromides-buliding-blocks, and the molecular formula is C7H7BrO2, Recommanded Product: 2-Bromo-3-methoxyphenol.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary