In 2019,European Journal of Organic Chemistry included an article by Esteves, Henrique A.; Darbem, Mariana P.; Pimenta, Daniel C.; Stefani, Helio A.. Related Products of 3395-91-3. The article was titled 《Carbonylative Negishi-Type Coupling of 2-Iodoglycals with Alkyl and Aryl Halides》. The information in the text is summarized as follows:
C-Glycosides are valuable organic compounds in the field of medicinal chem. due to their ubiquity inside living systems and pronounced biol. activity. Herein, we describe an approach to alkyl-ketones bearing glycal units, e.g. I, via the Pd-catalyzed carbonylative coupling of 2-iodoglycals and alkyl and aryl halides. Examples bearing a variety of functional groups are presented as well as a mechanistic proposal for this transformation. In the experiment, the researchers used Methyl 3-bromopropanoate(cas: 3395-91-3Related Products of 3395-91-3)
Methyl 3-bromopropanoate(cas: 3395-91-3) belongs to bromides. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon–bromine bond is electrophilic, i.e. alkyl bromides are alkylating agents.Related Products of 3395-91-3
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary