Quality Control of 1-Bromo-3,4,5-trimethoxybenzeneIn 2020 ,《In-depth examination of the pterolactams behaviour in Lewis/Bronsted acid catalysis environment: Total isolation of the reaction products》 appeared in ARKIVOC (Gainesville, FL, United States). The author of the article were Dumitriu, Gina-Mirabela; Bicu, Elena; Rigo, Benoit; Moncol, Jan; Daich, Adam; Ghinet, Alina. The article conveys some information:
To gain some insights on the amidoalkylation process, authors were interested in studying the product distribution when pterolactam was exposed to acids. The reactivity of pterolactam and its N-aryl derivatives towards TMSOTf or TfOH has been carefully examined in presence and absence of TMS-protected anilines. Under these conditions, the N-acyliminium precursors showed high reactivity at both α- and β-positions of the nitrogen atom. In this context, these salts can induce cascade processes including Povarov type reaction among other transformations. In that way, novel quinolines and tetrahydro-quinolines, among other compounds, were isolated for the first time.1-Bromo-3,4,5-trimethoxybenzene(cas: 2675-79-8Quality Control of 1-Bromo-3,4,5-trimethoxybenzene) was used in this study.
1-Bromo-3,4,5-trimethoxybenzene(cas: 2675-79-8) is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.Quality Control of 1-Bromo-3,4,5-trimethoxybenzene1-Bromo-3,4,5-trimethoxybenzene can be used to synthesize analogs of HA14-1, which shows promising anticancer properties.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary