《Copper-Catalyzed Construction of Trinuclear N-Fused Hybrid Scaffolds Using Cyclic Ureas as New Building Blocks》 was written by Dao, Pham Duy Quang; Cho, Chan Sik. Synthetic Route of C7H5BrOThis research focused ontrinuclear fused hetereocycle preparation cyclization benzimidazole cyclic urea. The article conveys some information:
2-(2-Bromoaryl)- and 2-(2-bromovinyl)-benzimidazoles are coupled and cyclized with cyclic ureas as new building blocks in DMF in the presence of a catalytic amount of a copper catalyst and a base to give the corresponding trinuclear N-fused hybrid scaffolds in good yields. Trinuclear N-fused hybrid scaffolds having methoxy group on benzimidazole moiety are readily oxidized to unprecedented benzimidazolequinone-fused hybrid scaffolds in high yields by treatment of ceric ammonium nitrate in acetonitrile/H2O.o-Bromobenzaldehyde(cas: 6630-33-7Synthetic Route of C7H5BrO) was used in this study.
o-Bromobenzaldehyde(cas: 6630-33-7) is used in L-threonine aldolase-catalyzed enantio/diastereoselective aldol reactions.Synthetic Route of C7H5BrOIt is also used in L-threonine aldolase-catalyzed enantio and diastereoselective aldol reactions. Further, it reacts with trichloromethane to prepare 1-(2-bromo-phenyl)-2,2,2-trichloro-ethanol.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary