Quality Control of Methyltriphenylphosphonium bromideIn 2021 ,《Asymmetric Total Synthesis of Dankasterones A and B and Periconiastone A Through Radical Cyclization》 appeared in Angewandte Chemie, International Edition. The author of the article were Chen, Pengquan; Wang, Cheng; Yang, Rui; Xu, Hongjin; Wu, Jinghua; Jiang, Huanfeng; Chen, Kai; Ma, Zhiqiang. The article conveys some information:
We describe herein the assembly of the cis-decalin framework through radical cyclization initiated by metal-catalyzed hydrogen atom transfer (MHAT), further applied it in the asym. synthesis of dankasterones A and B and periconiastone A. Position-selective C-H oxygenation allowed for installation of the necessary functionality. A radical rearrangement was adopted to create 13(14→8)abeo-8-ergostane skeleton. Interconversion of dankasterone B and periconiastone A was realized through biomimetic intramol. aldol and retro-aldol reactions. The MHAT-based approach, serves as a new dissection means, is complementary to the conventional ways to establish cis-decalin framework. In the experiment, the researchers used many compounds, for example, Methyltriphenylphosphonium bromide(cas: 1779-49-3Quality Control of Methyltriphenylphosphonium bromide)
Methyltriphenylphosphonium bromide(cas: 1779-49-3) is a lipophilic molecule with a cation allowing for it to be used to deliver molecules to specific cell components. Also considered an antineoplastic agent.Quality Control of Methyltriphenylphosphonium bromide
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary