Category: bromides-buliding-blocksOn March 31, 2021, Akhtar, Muhammad Saeed; Yang, Won-Guen; Kim, Sung Hong; Lee, Yong Rok published an article in Asian Journal of Organic Chemistry. The article was 《Organic-Inorganic Dual Catalytic System for the Regioselective Construction of Diverse Quinone Derivatives via Benzannulation》. The article mentions the following:
Efficient and regioselective synthesis of highly functionalized naphthoquinones I (R1 = Me, OMe, Ph; R2 = H, Me; R3 = H, Me, Ph; R4 = H, Me, 4-methylpent-3-en-1-yl; R5 = H, Et, 3-methylbut-2-en-1-yl, n-Bu, etc.) and II (R6 = H, Me) and anthraquinone derivatives III was accomplished in good yields using an organic-inorganic dual catalyst through [4+2] cycloaddition reaction between various 1,4-benzenediols 1-4-(OH)2-2-R1-3-R2C6H2 and benzonorbornene-3,6-diol/1,4-naphthalenediol and hydroquinone and α,β-unsaturated aldehydes R4C(CH2R5)=C(R3)CHO. These atom-economic reactions rapidly provided useful cycloaddition adducts in a one-pot reaction. The technique was successfully applied to synthesize tectoquinone, a natural compound found in red heartwood-type Cryptomeria japonica, and 2-(4-methylpent-3-enyl)anthracene-9,10-dione, found in the roots of Sesamum indicum, and their analogs. After reading the article, we found that the author used 2-Bromobenzene-1,4-diol(cas: 583-69-7Category: bromides-buliding-blocks)
2-Bromobenzene-1,4-diol(cas: 583-69-7) belongs to organobromine compounds.The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. Category: bromides-buliding-blocks Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary