Zhang, Xiaoyun; Yang, Yuan; Liang, Yun published the artcile< Palladium-catalyzed double N-arylation to synthesize multisubstituted dibenzoazepine derivatives>, Application of C8H4BrNO, the main research area is double arylation primary amine bisbromophenylethene palladium catalyst; dibenzoazepine preparation.
Palladium-catalyzed double N-arylation of primary amines with (Z)-1,2-bis(2-bromophenyl)ethenes was investigated. E.g., in presence of Pd2(dba)3 and DPEphos, double N-arylation of 4-FC6H4NH2 with (Z)-1,2-bis(2-bromophenyl)ethene gave 81% dibenzoazepine derivative (I). A variety of dibenzoazepine derivatives were synthesized in good to excellent yields.
Tetrahedron Letters published new progress about Arylation. 89003-95-2 belongs to class bromides-buliding-blocks, and the molecular formula is C8H4BrNO, Application of C8H4BrNO.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary