Siddiqui, I. R.; Rahila; Rai, Pragati; Sagir, Hozeyfa; Waseem, Malik A. published the artcile< Molecular iodine catalysed domino cyclization in aqueous medium: a simple and efficient synthetic route to 1,4-dihydropyridazines>, Formula: C9H7BrO, the main research area is dihydropyridazine preparation green chem; benzylidene phenylhydrazine unsaturated aldehyde cyclization iodine catalyst.
A facile, efficient and environmentally friendly approach has been developed for the diverse synthesis of 1,4-dihydropyridazines I (R = Ph, 4-ClC6H4, 4-MeOC6H4, 1-naphthyl, 4-bromonaphthyl; R1 = Me, Ph, 4-NCC6H4, 3-O2NC6H4, etc.) from (E)-2-benzylidene-1-phenylhydrazines and α,β-unsaturated aldehydes under aqueous condition using mol. iodine as a green and recoverable catalyst. This procedure features low cost and easily available starting materials, an inexpensive and recoverable catalyst, short reaction time, reliable scalability, excellent yield and mild reaction conditions, as well as use of aqueous medium. The scope of this method was thoroughly explored under three different reaction conditions resulting in the generation of a library of title compounds In view of the various advantages of the present investigation, this methodol. gives a convenient and straightforward pathway to construct 1,4-dihydropyridazines in an eco-friendly fashion.
RSC Advances published new progress about Cyclization. 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Formula: C9H7BrO.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary