Ranjini, P.; Shilpa, Chaitramallu M.; Kesagodu, Devaraju; Basavaraju, Y. B. published their research in World Journal of Pharmacy and Pharmaceutical Sciences in 2021. The article was titled 《Synthesis of substituted 6,7-dimethoxy-4-(3,4,5-trimethoxyphenyl)-3,4-dihydronaphthalen-1(2H)-one and their apoptosis study》.SDS of cas: 2675-79-8 The article contains the following contents:
The field of biomedical analogs of podophyllotoxin is more in its infancy, but the explosion of interest in these mols. as inherently active therapeutic agents is increasing. There is growing interest in the design and synthesis of novel biocompatible analogs. The series of novel substituted podophyllotoxin derivatives I (R1 = H, OCH3; R2 = H, OCH3, Cl, etc.) were synthesized under mild conditions with satisfactory yield. Auto dock server anal. of the these analogs structure showed that the compounds were shown to interact with the proteins involved in Bcl-xL mediated pathway with inhibition constant of 0.000149 and 0.000584 for I (R1 = H; R2 = NH2) and I (R1 = H; R2 = CH3) resp. The recorded results of lipid peroxidation with treated samples were increased with increasing concentration In the part of experimental materials, we found many familiar compounds, such as 1-Bromo-3,4,5-trimethoxybenzene(cas: 2675-79-8SDS of cas: 2675-79-8)
1-Bromo-3,4,5-trimethoxybenzene(cas: 2675-79-8) is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.SDS of cas: 2675-79-81-Bromo-3,4,5-trimethoxybenzene can be used to synthesize symmetric 3,3′,4,4′,5,5′-hexamethoxydiphenylacetylene via Stille-type coupling with bis-(tributylstannyl)acetylene.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary