Pearce-Higgins, Robert; Hogenhout, Larissa N.; Docherty, Philip J.; Whalley, David M.; Chuentragool, Padon; Lee, Najung; Lam, Nelson Y. S.; McGuire, Thomas M.; Valette, Damien; Phipps, Robert J. published the artcile< An Enantioselective Suzuki-Miyaura Coupling To Form Axially Chiral Biphenols>, COA of Formula: C7H7BrO2, the main research area is arylbromide phenylboronate ester palladium sSPhos catalyst Suzuki Miyaura coupling; arylphenol enantioselective preparation.
The use of enantiopure, sulfonated SPhos (sSPhos), an existing ligand that has until now been used only in racemic form and that derived its chirality from an atropisomeric axis that was introduced through sulfonation. The attractive noncovalent interactions involving the ligand sulfonate group was responsible for the high levels of asym. induction that we obtain in the 2,2′-biphenol products of Suzuki-Miyaura coupling, and a highly practical resolution of sSPhos via diastereomeric salt recrystallization was developed.
Journal of the American Chemical Society published new progress about Aryl bromides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 135999-16-5 belongs to class bromides-buliding-blocks, and the molecular formula is C7H7BrO2, COA of Formula: C7H7BrO2.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary