Moon, Patrick J.; Yin, Shengkang; Lundgren, Rylan J. published the artcile< Ambient Decarboxylative Arylation of Malonate Half-Esters via Oxidative Catalysis>, Related Products of 14062-30-7, the main research area is monoaryl acetate preparation; decarboxylative arylation coupling arylboron nucleophile malonic acid.
We report decarboxylative carbonyl α-arylation by coupling of arylboron nucleophiles with malonic acid derivatives This process is enabled by the merger of aerobic oxidative Cu catalysis with decarboxylative enolate interception reminiscent of malonyl-CoA reactivity in polyketide biosynthesis. This method enables the synthesis of monoaryl acetate derivatives containing electrophilic functional groups that are incompatible with existing α-arylation reactivity paradigms. The utility of the reaction is demonstrated in drug intermediate synthesis and late-stage functionalization.
Journal of the American Chemical Society published new progress about Arylation. 14062-30-7 belongs to class bromides-buliding-blocks, and the molecular formula is C10H11BrO2, Related Products of 14062-30-7.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary