Lin, Shuangzheng; Zhao, Gui-Ling; Deiana, Luca; Sun, Junliang; Zhang, Qiong; Leijonmarck, Hans; Cordova, Armando published the artcile< Dynamic kinetic asymmetric domino oxa-Michael/carbocyclization by combination of transition-metal and amine catalysis: catalytic enantioselective synthesis of dihydrofurans>, Recommanded Product: 3-(4-Bromophenyl)acrylaldehyde, the main research area is dihydrofuran derivative enantioselective synthesis; propargyl alc enal Michael carbocyclization chiral amine; transition metal catalyst reduction oxidation epoxidation.
An unprecedented highly enantioselective domino oxa-Michael/carbocyclization between propargyl alcs. and enals by combination of asym. amine and transition-metal catalysis has been developed. The DYKAT gives access to valuable dihydrofurans I (R = 4-NO2-C6H4, 4-CN-C6H4, 3-NO2-C6H4, 4-Br-C6H4, 4-Cl-C6H4, Ph, 4-Me-C6H4, 2-naphtheyl, 4-F-C6H4, nPr) in good to high yields with e.r. of up to 99.5 :0.5. The reduction of I (R = 2-naphthyl, 4-Cl-C6H4) yields alcs. Oxidation or epoxidation reactions are investigated.
Chemistry – A European Journal published new progress about Alcohols, propargyl Role: RCT (Reactant), RACT (Reactant or Reagent). 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Recommanded Product: 3-(4-Bromophenyl)acrylaldehyde.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary