Kumar, Sandeep; Gupta, Sujeet Kumar published their research in World Journal of Pharmacy and Pharmaceutical Sciences in 2021. The article was titled 《Synthesis, characterization & biological activity of some N9 -(arylidene acetylhydrazino)-carbazole novel carbazole derivative》.Application of 6630-33-7 The article contains the following contents:
Synthesized six new derivatives of carbazole I[ R = 4-Cl, 4-NO2, 3-Br] test them for their anti-inflammatory activity using the carrageenan induced inflammation model in rat paw edema model. In scheme synthesized N-(chloroacetyl)-carbazole then react with hydrazine hydrate to give N-(hydrazinoacetyl)-carbazole were further reacted with various substituted aldehyde in the presence of ethanol and dioxan and found to six derivative of carbazole I. The structure of final product were confirmed by FTIR and 1H NMR. Value of FTIR, 1H NMR and thin layer chromatog. were found to be significant. All biol. activity screening by carrageenan induced inflammation in rat hind paw edema model. The compound I[ R = 3-Cl, 2-Br] most potent compound with compared to Diclofenc.o-Bromobenzaldehyde(cas: 6630-33-7Application of 6630-33-7) was used in this study.
o-Bromobenzaldehyde(cas: 6630-33-7) is used in L-threonine aldolase-catalyzed enantio/diastereoselective aldol reactions.Application of 6630-33-7It is a key starting material in the total synthesis of an anticancer agent, (-)-taxol.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary