Ibrahem, Ismail; Breistein, Palle; Cordova, Armando published the artcile< One-Pot Three-Component Highly Selective Synthesis of Homoallylboronates by Using Metal-Free Catalysis>, Application In Synthesis of 3893-18-3, the main research area is homoallylboronate preparation catalyst imidazolium amine tandem reaction stereoselective; pinacolboron tandem unsaturated aldehyde phosphoranylidene catalyst imidazolium amine stereoselective.
The authors have developed the 1st metal-free 1-pot three-component catalytic selective reaction between a diboron reagent, α,β-unsaturated aldehydes, and 2-(triphenylphosphoranylidene)acetate esters. The multicomponent reactions proceed with high chemo- and regioselectivity through a catalytic β-boration/Wittig sequence, which gives the corresponding homoallylboronates in 59% to 63% yield by using simple bench-stable N-heterocyclic carbenes and amines as catalysts. In addition, a novel merging of the catalytic cycles of NHC nucleophilic activation of diboron reagents and amine-catalyzed iminium activation of enals was disclosed. Further development of this type of 1-pot multicomponent catalytic reactions, enantioselective variants, and its application in total synthesis is ongoing in the authors’ laboratories
Chemistry – A European Journal published new progress about 1,2-Addition reaction. 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Application In Synthesis of 3893-18-3.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary