Hu, Wei; Zeng, Qiang; Chen, Weiming published the artcile< Improved Synthesis of First Cell-Permeable Allosteric PTPRZ Inhibitor NAZ2329>, COA of Formula: C7H4BrF3O, the main research area is protein tyrosine phosphatase receptor allosteric inhibitor preparation antitumor activity.
NAZ2329 is the first cell-permeable small mol. allosteric inhibitor of protein tyrosine phosphatase receptor-type Z (PTPRZ), which was considered as a new potential mol. target for drug development in glioblastoma. A facile and high-efficient synthesis of NAZ2329 was developed by a straight-forward strategy starting from key ethoxy benzyl bromide intermediate obtained from com. available 4-(trifluoromethyl)phenol.
Russian Journal of General Chemistry published new progress about Antitumor agents. 81107-97-3 belongs to class bromides-buliding-blocks, and the molecular formula is C7H4BrF3O, COA of Formula: C7H4BrF3O.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary