Galli, Marzia; Fletcher, Catherine J.; del Pozo, Marc; Goldup, Stephen M. published the artcile< Scalable anti-Markovnikov hydrobromination of aliphatic and aromatic olefins>, COA of Formula: C8H8BrF, the main research area is alkene hydrogen bromide regioselective hydrobromination; alkyl bromide preparation.
To improve access to a key synthetic intermediate a direct hydrobromination-Negishi route was targeted. Unsurprisingly, the anti-Markovnikov addition of HBr to estragole in the presence of AIBN proved successful. However, even in the absence of an added initiator, anti-Markovnikov addition was observed Re-examination of early reports revealed that selective Markovnikov addition, often simply termed “”normal”” addition, was not always observed with HBr unless air was excluded, leading to the rediscovery of a reproducible and scalable initiator-free protocol.
Organic & Biomolecular Chemistry published new progress about Alkenes Role: RCT (Reactant), RACT (Reactant or Reagent). 405931-46-6 belongs to class bromides-buliding-blocks, and the molecular formula is C8H8BrF, COA of Formula: C8H8BrF.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary