In 2022,Chemical Communications (Cambridge, United Kingdom) included an article by Deng, Zhixin; Han, Sheng; Ke, Miaolin; Ning, Yingtang; Chen, Fen-Er. Safety of Ethyl 3-(2-bromophenyl)propanoate. The article was titled 《Ligand-enabled palladium-catalyzed hydroesterification of vinyl arenes with high linear selectivity to access 3-arylpropanoate esters》. The information in the text is summarized as follows:
Palladium-catalyzed linear-selective hydroesterification of vinyl arenes with alcs. enabled by diphosphine ligands derived from bis[2-(diphenylphosphino)ethyl]amides has been developed. A variety of 3-arylpropanoate esters were obtained in high yields and regioselectivity. The robustness of this methodol. was further demonstrated by the efficient gram-scale synthesis of the Et 3-phenylpropanoate as a precursor to hydrocinnamic acid. After reading the article, we found that the author used Ethyl 3-(2-bromophenyl)propanoate(cas: 135613-33-1Safety of Ethyl 3-(2-bromophenyl)propanoate)
Ethyl 3-(2-bromophenyl)propanoate(cas: 135613-33-1) belongs to organobromine compounds.The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.Safety of Ethyl 3-(2-bromophenyl)propanoate
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary