Boelke, Andreas; Kuczmera, Thomas J.; Caspers, Lucien D.; Lork, Enno; Nachtsheim, Boris J. published the artcile< Iodolopyrazolium Salts: Synthesis, Derivatizations and Applications>, Computed Properties of 20776-50-5, the main research area is oxidative cyclization iodophenylpyrazole; iodolopyrazolium triflate preparation.
The synthesis of iodolopyrazolium triflates via an oxidative cyclization of 3-(2-iodophenyl)-1H-pyrazoles is described. The reaction is characterized by a broad substrate scope, and various applications of these novel cyclic iodonium salts acting as useful synthetic intermediates are demonstrated, in particular in site-selective ring openings. This was finally applied to generate derivatives of the anti-inflammatory drug celecoxib. Their application as highly active halogen-bond donors is shown as well.
Organic Letters published new progress about Oxidative cyclization. 20776-50-5 belongs to class bromides-buliding-blocks, and the molecular formula is C7H6BrNO2, Computed Properties of 20776-50-5.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary