Application In Synthesis of Benzyl 2-bromoacetateIn 2020 ,《E- and chemoselective thia-Michael addition to benzyl allenoate》 was published in Phosphorus, Sulfur and Silicon and the Related Elements. The article was written by Bibi, Rifhat; Murtaza, Amna; Khan, Khalid Mohammed; Rehman, Zia ur; Saeed, Aamer; Tahir, Muhammad Nawaz; Hassan, Abbas. The article contains the following contents:
Different thiols were successfully reacted with benzyl allenoate resulting in E-selective thia-Michael addition product with α,β-unsaturation as confirmed by single crystal x-ray crystallog. anal. The thia-Michael addition was chemoselective and free amine and alc. groups were well tolerated. Catalytic triethylamine was required for high conversion. Fair to excellent yields were obtained for a variety of aliphatic, aryl and heteroaryl thiols. After reading the article, we found that the author used Benzyl 2-bromoacetate(cas: 5437-45-6Application In Synthesis of Benzyl 2-bromoacetate)
Benzyl 2-bromoacetate(cas: 5437-45-6) has been used in the alkylation of (-)-2,3-O-isopropylidene-D-threitol that afforded lipopeptide, 2-[(4R,5R)-5-({[(9H-fluoren-9-yl)methoxy]carbonylaminomethyl}-2,2-dimethyl-1,3-dioxolan-4-yl)methoxy]acetic acid.Application In Synthesis of Benzyl 2-bromoacetate
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary