Belokon’, Yuri N.; Davies, R. Gareth; Fuentes, Jose A.; North, Michael; Parsons, Teresa published the artcile< The influence of imine structure, catalyst structure and reaction conditions on the enantioselectivity of the alkylation of alanine methyl ester imines catalyzed by Cu(ch-salen)>, Application In Synthesis of 81107-97-3, the main research area is alaninate imine preparation stereoselective alkylation copper salen catalyst.
Systematic variation of the substrate structure has shown that the most effective substrates for Cu(ch-salen)-catalyzed asym. enolate alkylation reactions carried out under phase-transfer conditions are the p-chlorophenyl imines of amino esters. The other reaction parameters (solvent and stirring speed) have also been optimized. The introduction of substituents onto the aryl rings of the salen ligand was found not to have a beneficial effect on the enantioselectivity of the reaction.
Tetrahedron Letters published new progress about Alkylation catalysts. 81107-97-3 belongs to class bromides-buliding-blocks, and the molecular formula is C7H4BrF3O, Application In Synthesis of 81107-97-3.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary