Alba, Andrea-Nekane; Companyo, Xavier; Moyano, Albert; Rios, Ramon published the artcile< Formal Highly Enantioselective Organocatalytic Addition of Fluoromethyl Anion to α,β-Unsaturated Aldehydes>, Safety of 3-(4-Bromophenyl)acrylaldehyde, the main research area is unsaturated aldehyde fluorobisphenylsulfonyl methane chiral diphenylprolinol TMS ether; enantioselective nucleophilic addition fluorobisphenylsulfonylmethyl aldehyde stereoselective preparation reduction oxidation; reductive amination alc carboxylic acid amine stereoselective preparation; esterification reductive desulfonylation ester fluoroalc stereoselective preparation; oxidation fluoroaldehyde stereoselective preparation DEAD amination reduction aminoalc; nucleophilic addition enantioselective catalyst chiral diphenylprolinol TMS ether.
The first organocatalytic enantioselective fluoro(bisphenylsulfonyl)methylation od α,β-unsaturated aldehydes in high yields and enantioselectivities was described. The resulting compounds were converted into a wide range of derivatives to show the applicability of this new methodol. Moreover, valuable 4-fluoro-2-amino-1-alkanol that can be easily transformed to fluoroaminoacids or fluoroaminoalcs. by know procedures was synthesized.
Chemistry – A European Journal published new progress about Aldehydes, halo Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Safety of 3-(4-Bromophenyl)acrylaldehyde.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary