Thun-Hohenstein, Siegfried T. D.; Suits, Timothy F.; Malla, Tika R.; Tumber, Anthony; Brewitz, Lennart; Choudhry, Hani; Salah, Eidarus; Schofield, Christopher J. published the artcile< Structure-Activity Studies Reveal Scope for Optimisation of Ebselen-Type Inhibition of SARS-CoV-2 Main Protease>, Formula: C7H4Br2O2, the main research area is ebselen derivative SARS CoV2 main protease inhibitor COVID19; COVID-19; Mpro inhibition; SARS-CoV-2; ebselen; ebsulfur; nucleophilic cysteine protease..
The reactive organoselenium compound ebselen is being investigated for treatment of coronavirus disease 2019 (COVID-19) and other diseases. We report structure-activity studies on sulfur analogs of ebselen with the Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro), employing turnover and protein-observed mass spectrometry-based assays. The results reveal scope for optimization of ebselen/ebselen derivative- mediated inhibition of Mpro, particularly with respect to improved selectivity.
ChemMedChem published new progress about Anticoronaviral agents. 603-78-1 belongs to class bromides-buliding-blocks, and the molecular formula is C7H4Br2O2, Formula: C7H4Br2O2.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary