Messina, Cynthia; Douglas, Liam Z.; Liu, Jiang Tian; Forgione, Pat published the artcile< Successive Pd-Catalyzed Decarboxylative Cross-Couplings for the Modular Synthesis of Non-Symmetric Di-Aryl-Substituted Thiophenes>, COA of Formula: C7H7BrO2S, the main research area is thiophene ester heteroaromatic acid aryl bromide cross coupling palladium; non sym thiophene preparation.
Oligothiophenes are important organic mols. in a number of burgeoning industries as semi-conducting materials due to their extensive π-conjugation and charge transport properties. Typically, non-sym., di-aryl-substituted thiophenes are prepared by the successive formation of Grignards, organotin, and/or boronic acid intermediates that can be subsequently employed in cross-coupling reactions. While reliable, these approaches present synthetic difficulties due to the reactivity of organo-metallic/pseudo-metallic species, and produce considerable amounts of waste due to necessary pre-functionalization. We have developed a decarboxylative cross-coupling route as an effective strategy for the modular and less wasteful synthesis of a wide range of non-sym., di-arylthiophenes, e.g., I. This method uses a thiophene ester building block for successive decarboxylative palladium-catalyzed couplings that allows for the efficient synthesis and evaluation of the optoelectronic properties of a library of candidate semi-conductors with functional groups that could be challenging to access using previous routes.
European Journal of Organic Chemistry published new progress about Absorption spectra. 5751-83-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H7BrO2S, COA of Formula: C7H7BrO2S.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary