Meazza, Marta; Leth, Lars A.; Erickson, Jeremy D.; Jorgensen, Karl Anker published the artcile< Indium(III)-catalyzed Aza-Conia-Ene Reaction for the Synthesis of Indolizines>, Recommanded Product: 3-(4-Bromophenyl)acrylaldehyde, the main research area is indolizine pyrroloquinoline preparation aza Conia ene cyclization indium catalyst; heterocycles; indium; indolizines; synergistic catalysis.
A new indium(III)-catalyzed reaction for the synthesis of a series of indolizine scaffolds has been developed. This methodol. was highly efficient, allowing a low catalyst loading of 2 mol % (down to 0.5 mol %) and rendering the products in high yields through a 5-exo-dig aza-Conia-ene reaction. Furthermore, the possibility of incorporating an electrophile into the generated pyrrolidone ring in a one-pot synergistic fashion was demonstrated. Finally, based on exptl. observations, a mechanism proposal was outlined.
Chemistry – A European Journal published new progress about Enantioselective synthesis. 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Recommanded Product: 3-(4-Bromophenyl)acrylaldehyde.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary