Li, Pinyi; Jia, Xiuwen; Ma, Xiaoli; Ma, Wenbo; Sheng, Yilin; Zhao, Jingwei; Zhao, Fei published the artcile< A Catalyst-Free Cascade Reaction for the Selective Assembly of 3-Hydroxyisoindolinones on Water>, Related Products of 3959-07-7, the main research area is hydroxyisoindolinone green preparation; alkynylbenzoic acid nitrogen nucleophile cascade.
A catalyst- and additive-free cascade reaction between 2-alkynylbenzoic acids and nitrogen-containing nucleophiles for the selective assembly of 3-hydroxyisoindolinones I [R1 = H, 4-Me, 6-F, etc.; R2 = H, n-Bu, Ph, etc.; R3 = n-Bu, Ph, Bn, etc.] under water was developed. This protocol featured readily available starting materials, an environmentally benign solvent, simple operation, extraordinarily broad substrate scope, good functional group tolerance, excellent selectivity, good to excellent yields, high atom- and step-economy, and high bond-forming efficiency, thus provided a convenient and highly efficient access to 3-hydroxyisoindolinones I.
Asian Journal of Organic Chemistry published new progress about Alkynes, aryl Role: RCT (Reactant), RACT (Reactant or Reagent). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Related Products of 3959-07-7.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary