Ge, Liang; Wang, Ding-Xing; Xing, Renyi; Ma, Di; Walsh, Patrick J.; Feng, Chao published the artcile< Photoredox-catalyzed oxo-amination of aryl cyclopropanes>, Application of C21H22BrP, the main research area is aryl cyclopropane azole iridium photocatalyst ring opening oxidative amination; azolylalkyl ketone regioselective preparation.
A photoredox-coupled ring-opening oxo-amination of electronically unbiased cyclopropanes, which enabled the expedient construction of a host of structurally diverse β-amino ketone derivatives Through one electron oxidation, the relatively inert aryl cyclopropanes were readily converted into reactive radical cation intermediates, which in turn participate in the ensuing ring-opening functionalizations. Based on mechanistic studies, the present oxo-amination was proposed to proceed through an SN2-like nucleophilic attack/ring-opening manifold. This protocol featured wide substrate scope, mild reaction conditions, and use of dioxygen as an oxidant both for catalyst regeneration and oxygen-incorporation. Moreover, a one-pot formal aminoacylation of olefins was described through a sequential cyclopropanation/oxo-amination.
Nature Communications published new progress about Aminoacylation (regioselective). 1530-33-2 belongs to class bromides-buliding-blocks, and the molecular formula is C21H22BrP, Application of C21H22BrP.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary