Li, Huiqiong; Feng, Huangdi; Zhang, Jingxian; Van der Eycken, Erik V.; Huang, Liliang published the artcile< Synthetic Access to Secondary Propargylamines via a Copper-Catalyzed Oxidative Deamination/Alkynylation Cascade>, HPLC of Formula: 3959-07-7, the main research area is amine alkyne deaminative coupling alkynylation copper; secondary propargylamine preparation; copper deaminative coupling alkynylation catalyst.
A selective cascade reaction of primary amines and alkynes for the synthesis of the corresponding secondary propargylamines is described. This protocol proceeds with a CuBr2/TBHP system through a process of oxidative deamination of primary amines to imine and alkynylation, featuring a wide scope of substrates with good functional-group tolerance and operational simplicity. Addnl., the use of two different primary amines could also work smoothly using this protocol.
Journal of Organic Chemistry published new progress about Alkynes Role: RCT (Reactant), RACT (Reactant or Reagent). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, HPLC of Formula: 3959-07-7.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary