Bai, Xueying; Huang, Liliang; Qing, Bin; Zuo, Zhicheng; Feng, Huangdi published the artcile< Catalyst-Free Hydrogen Proton Transfer Reduction of Nitrobenzamides to Aminobenzamides with i-PrOH/KOH System>, Computed Properties of 3959-07-7, the main research area is aminobenzamide preparation chemoselective; nitrobenzamide hydrogen proton transfer reduction.
A reduction of nitrobenzenes via the combination of KOH and isopropanol was established for the general synthesis of aniline derivatives A metal catalyst isn’t required in this alternative reduction reaction, and a series of nitrobenzamide compounds RC6H4C(O)NHR1 (R = 2-NO2, 3-NO2, 4-NO2; R1 = 4-bromobenzyl, 2,6-diisopropylphenyl, 3-methoxybenzyl, etc.) were chemoselectively reduced into the corresponding aminobenzamides RC6H4C(O)NHR1 (R = 2-NH2, 3-NH2, 4-NH2) in good to excellent yields. This reaction is operationally simple, and proceeds under mild conditions.
Asian Journal of Organic Chemistry published new progress about Aromatic amines Role: SPN (Synthetic Preparation), PREP (Preparation). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Computed Properties of 3959-07-7.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary