Tietze, Lutz F.; Hungerland, Tim; Duefert, Alexander; Objartel, Ina; Stalke, Dietmar published the artcile< Synthesis of tetrasubstituted alkenes through a palladium-catalyzed domino carbopalladation/C-H-activation reaction>, Name: 2-Bromo-4-(trifluoromethyl)phenol, the main research area is helical tetrasubstituted alkene preparation; propargylic alc preparation domino carbopalladation bond activation.
Helical tetrasubstituted alkenes, e.g., I, were obtained in a highly efficient way through a palladium-catalyzed domino-carbopalladation/C-H-activation reaction of propargylic alcs., e.g., II, in good to excellent yields. Electron-withdrawing- and electron-donating substituents can be introduced onto the upper and lower aromatic rings. The substrates for the domino process were synthesized by addition of the lithiated alkyne to various aldehydes; moreover, the substrates were accessible enantioselectively (in 95 % ee) by reduction of the corresponding ketone using the Noyori procedure.
Chemistry – A European Journal published new progress about Alcohols, propargyl Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 81107-97-3 belongs to class bromides-buliding-blocks, and the molecular formula is C7H4BrF3O, Name: 2-Bromo-4-(trifluoromethyl)phenol.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary