Takahashi, Rikuro; Seo, Tamae; Kubota, Koji; Ito, Hajime published the artcile< Palladium-Catalyzed Solid-State Polyfluoroarylation of Aryl Halides Using Mechanochemistry>, Application of C8H5BrS2, the main research area is polyfluorinated arylboronic acid pinacol ester Suzuki Miyaura coupling palladium.
The Suzuki-Miyaura cross-coupling between polyfluorinated arylboron nucleophiles and aryl halides enables the efficient construction of polyfluorinated structural motifs frequently found in organic materials and catalysts. A key challenge associated with this transformation involves the slow transmetalation with weakly nucleophilic polyfluorinated organoboron reagents, which often reduces the yield of the coupling products. Here, authors show that solid-state high-temperature ball-milling conditions facilitate a palladium-catalyzed cross-coupling with polyfluorinated arylboronic acids and pinacol esters employing a simple catalytic system in the absence of any stoichiometric additives. This reaction exhibits a broad substrate scope and can be carried out in air, and the use of large amounts of dry and degassed organic solvents is not required. The successful cross-coupling of weakly nucleophilic polyfluorinated organoboron reagents was ascribed to the extremely high concentrations of the substrates and the catalyst under solid-state conditions.
ACS Catalysis published new progress about Arylation (polyfluoro-). 3480-11-3 belongs to class bromides-buliding-blocks, and the molecular formula is C8H5BrS2, Application of C8H5BrS2.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary