Messina, Cynthia; Ottenwaelder, Xavier; Forgione, Pat published the artcile< Programmed Synthesis of Tetra-Aryl Thiophenes with Stepwise, Ester-Controlled Regioselectivity>, HPLC of Formula: 5751-83-7, the main research area is tetraaryl thiophene preparation.
Herein, a modular synthetic route to access tetra-arylated thiophene compounds with four different substituents with programmed chem. control provided by an ester activating/directing group was reported. This method enables the functionalization of individual positions of thiophene sequentially via regioselective halogenations and cross-coupling reactions. The reaction sequence described provides tetra-arylated thiophenes in higher yields than previous routes and employs practical reaction protocols, simple catalytic systems and short reaction times.
Organic Letters published new progress about Bromination, regioselective. 5751-83-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H7BrO2S, HPLC of Formula: 5751-83-7.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary