Liu, Yingpeng; Ho, Thanh C.; Baradwan, Mohammed; Lopez-Alberca, Maria Pascual; Iliopoulos-Tsoutsouvas, Christos; Nikas, Spyros P.; Makriyannis, Alexandros published the artcile< Synthesis of functionalized cannabilactones>, Recommanded Product: Methyl 2-bromo-4-methoxybenzoate, the main research area is cannabilactone Suzuki cross coupling reaction; CB2 selective ligands; Suzuki cross-coupling; cannabilactones; cannabinoids.
A new approach to synthesize cannabilactones using Suzuki cross-coupling reaction followed by one-step demethylation-cyclization is presented. The two key cannabilactone prototypes AM1710 and AM1714 were obtained selectively in high overall yields and in a lesser number of synthetic steps when compared to our earlier synthesis. The new approach expedited the synthesis of cannabilactone analogs with structural modifications at the four potential pharmacophoric regions.
Molecules published new progress about Cyclization. 17100-65-1 belongs to class bromides-buliding-blocks, and the molecular formula is C9H9BrO3, Recommanded Product: Methyl 2-bromo-4-methoxybenzoate.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary