Liu, Yao-Zong; Zhang, Jie; Xu, Peng-Fei; Luo, Yong-Chun published the artcile< Organocatalytic Asymmetric Michael Addition of 1-Acetylindolin-3-ones to α,β-Unsaturated Aldehydes: Synthesis of 2-Substituted Indolin-3-ones>, COA of Formula: C9H7BrO, the main research area is indolinone enantioselective preparation; acetylindolinone unsaturated aldehyde asym Michael addition diarylprolinol trimethylsilylether catalyst.
A highly efficient asym. Michael addition of 1-acetylindolin-3-ones to α,β-unsaturated aldehydes is developed to afford 2-substituted indolin-3-one derivatives, e.g., I, in high yields (up to 94%) with good stereoselectivities (up to 11:1 dr and 96% ee). The Michael adducts can be transformed into substituted cyclopentyl[b]indoline compounds conveniently without racemization.
Journal of Organic Chemistry published new progress about Enantioselective synthesis. 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, COA of Formula: C9H7BrO.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary