Koziakov, Denis; Majek, Michal; Jacobi von Wangelin, Axel published the artcile< Radical Aromatic Trifluoromethylthiolation: Photoredox Catalysis vs. Base Mediation>, Safety of (3-Bromophenyl)(trifluoromethyl)sulfane, the main research area is aryl trifluoromethyl sulfide preparation; arenediazonium salt bistrifluoromethyl disulfide photoredox trifluoromethylthiolation.
Trifluoromethyl aryl sulfides (Ar-SCF3) constitute highly attractive building blocks due to their exceptional lipophilicity and chem. properties. Related protocols of radical aromatic trifluoro-methylthiolation of arenediazonium salts were developed that are based on the facile generation of intermediate aryl radicals. Their reactions with com. F3CS-SCF3 under very mild conditions afforded a diverse set of Ar-SCF3 (< 90 % yield). Direct comparison of photoredox catalysis {eosin Y or [Ru(bpy)3]Cl2} with the weak base-mediated dark reaction documented higher synthetic efficiency of the former but higher operational simplicity of the latter strategy. European Journal of Organic Chemistry published new progress about Diazonium compounds, arene, salts Role: RCT (Reactant), RACT (Reactant or Reagent). 2252-45-1 belongs to class bromides-buliding-blocks, and the molecular formula is C7H4BrF3S, Safety of (3-Bromophenyl)(trifluoromethyl)sulfane.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary