Jiang, Lin; Jin, Wen-Fei; Yu, Liu-Dong; Yuan, Ming-Wei; Li, Hong-Li; Jiang, Deng-Bang; Yuan, Ming-Long published the artcile< Regioselective synthesis of benzonitriles via amino-catalyzed [3+3] benzannulation reaction>, Application of C9H7BrO, the main research area is arylsulfonyl biphenyl carbonitrile preparation green chem regioselective pyrrolidine catalyst; unsaturated aldehyde arylsulfonyl butenenitrile benzannulation.
A straightforward synthesis of benzonitriles I (Ar = Ph, p-ClC6H4, m-NO2-C6H4, etc.; Ar1 = Ph, p-Tol) is achieved via amino-catalyzed [3+3] benzannulation of α,β-unsaturated aldehydes and 4-arylsulfonyl-2-butenenitriles. Using pyrrolidine as an organocatalyst via iminium activation, a series of substituted benzonitriles were obtained in good to high yields in a regioselective manner. This reaction can proceed smoothly under mild reaction conditions and without the aid of any metals, addnl. oxidants, or strong bases, thus making this an efficient and environmentally friendly method to access benzonitriles.
Journal of Chemical Research published new progress about Aromatic nitriles Role: SPN (Synthetic Preparation), PREP (Preparation). 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Application of C9H7BrO.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary