Daili, Farah; Ouarti, Abdelhakim; Pinaud, Marine; Kribii, Ibtihal; Sengmany, Stephane; Le Gall, Erwan; Leonel, Eric published the artcile< Nickel-Catalyzed Electrosynthesis of Aryl and Vinyl Phosphinates>, Synthetic Route of 401-78-5, the main research area is nickel catalyst electrochem coupling aryl vinyl bromide phosphinate; aryl vinyl phosphinate preparation.
A mild and useful nickel-catalyzed electrochem. phosphonylation of aryl and vinyl bromides is described. We show that alkyl H-phenylphosphinates can be coupled electrochem. with functionalized aryl and vinyl bromides using very simple conditions (Fe/Ni anode, bench-stable nickel pre-catalyst, undivided cell, galvanostatic electrolysis) to furnish the corresponding aryl and vinyl phosphinates in satisfactory to good yields. Couplings can also be applied to heteroaromatic bromides with some limitations like increased propensity to hydro-dehalogenation.
European Journal of Organic Chemistry published new progress about Aryl bromides Role: RCT (Reactant), RACT (Reactant or Reagent). 401-78-5 belongs to class bromides-buliding-blocks, and the molecular formula is C7H4BrF3, Synthetic Route of 401-78-5.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary