Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 244205-40-1, formula is C6H6BBrO2, The most pervasive is the naturally produced bromomethane. Recommanded Product: (2-Bromophenyl)boronic acid
Dekkiche, Herve;Malincik, Juraj;Prescimone, Alessandro;Haussinger, Daniel;Mayor, Marcel research published 《 An Ortho-Tetraphenylene-Based “Gelander” Architecture Consisting Exclusively of 52 sp2-Hybridized C Atoms》, the research content is summarized as follows. A new type of “Gelander” mol. based on a ortho-tetraphenylene core is presented. The central para-quaterphenyl backbone is wrapped by a 4,4′-di((Z)-styryl)-1,1′-biphenyl banister, with its aryl rings covalently attached to all four Ph rings of the backbone. The resulting helical chiral bicyclic architecture consists exclusively of sp2-hybridized carbon atoms. The target structure was assembled by expanding the central ortho-tetraphenylene subunit with the required addnl. Ph rings followed by a twofold macrocyclization. The first macrocyclization attempts based on a twofold McMurry coupling were successful but low yielding; the second strategy, profiting from olefin metathesis, provided satisfying yields. Hydrogenation of the olefins resulted in a saturated derivative of similar topol., thereby allowing the interdependence between saturation and physico-chem. properties to be studied. The target structures, including their solid-state structures, were fully characterized. The helical chiral bicycle was synthesized as a racemate and separated into pure enantiomers by HPLC on a chiral stationary phase. Comparison of recorded and simulated chiroptical properties allowed the enantiomers to be assigned.
244205-40-1, 2-Bromophenylboronic Acid is used as an inhibitor of the hormone sensitive lipase.
2-Bromophenylboronic acid, also known as 2-Bromophenylboronic acid, is a useful research compound. Its molecular formula is C6H6BBrO2 and its molecular weight is 200.83 g/mol. The purity is usually 95%.
2-Bromophenylboronic acid is a glucose monitoring agent that has a ruthenium complex with an acidic environment. The nitro group and the amines are in close proximity to the boron center, and this proximity leads to a high nucleophilic character of the molecule. This reactivity allows 2-bromophenylboronic acid to be used as a fluorescence probe for acidic environments. 2-Bromophenylboronic acid also inhibits secretase enzymes, which are involved in Alzheimer’s disease and other neurodegenerative disorders. It is an inhibitor of γ-secretase, which is responsible for cleaving the amyloid precursor protein (APP), and it has shown efficacy against biphenyl, an anticancer drug that binds to benzodiazepine receptors. 2-Bromophenylboronic acid is also an enantiopure compound because all four substituents are different from each other., Recommanded Product: (2-Bromophenyl)boronic acid
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary