Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 6911-87-1, formula is C7H8BrN, Name is 4-Bromo-N-methylaniline. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Synthetic Route of 6911-87-1.
Chen, Jiaming;Wang, Fang;Huang, Yanping;Jia, Xiaoqi;Zhuang, Dailin;Wan, Zhenyang;Li, Ziyuan research published 《 Remote carbamate-directed site-selective benzylic C-H oxygenation via synergistic copper/TEMPO catalysis at room temperature》, the research content is summarized as follows. Synthesis of benzylic C(sp3)-H oxygenation RNHC(O)R1 (R = 4-butylphenyl, 4-butyl-2-fluorophenyl, 2,4-dibutyl-5-ethylphenyl, etc.; R1 = hexyloxidanyl, Me, allyl, etc.) with water at room temperature through a ligand- and additive-free synergistic copper/TEMPO-catalyzed radical relay pathway with N-fluorobenzenesulfonimide (NFSI) as a terminal oxidant is disclosed. With the assistance of carbamate directing groups, this oxygenation takes place site-selectively at the para-positions of the directing groups when multiple benzyl sites are available in a substrates. Mechanistic studies reveal the crucial role of catalytic TEMPO as a recyclable SET reductant, as well as the significance of the combined synergistic catalysis and remote directing strategy to the excellent chemoselectivity and site-selectivity. It has also been demonstrated that this novel strategy is promising for future studies on C(sp3)-H functionalization.
6911-87-1, 4-Bromo-N-methylaniline is a aniline based compound known to exhibit mutagenic properties.
4-Bromo-N-methylaniline is a useful research compound. Its molecular formula is C7H8BrN and its molecular weight is 186.05 g/mol. The purity is usually 95%.
4-Bromophenylmethylamine is an organic compound that has anti-inflammatory properties and is used as a pharmaceutical. It belongs to the group of amines. The hydrolysis of 4-bromophenylmethylamine by hydrochloric acid produces phenol and bromamine (NHBr). The reaction system can be used to synthesize a number of compounds, including anilines, benzofurans, and other aromatic compounds. 4-Bromophenylmethylamine reacts with muscle tissue in a similar manner as acetaminophen does. This drug also has been shown to have significant effects on the energy metabolism in the muscles of rats that are given carbon source., Synthetic Route of 6911-87-1
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary