Brzeskiewicz, Jakub team published research on Organic Letters in 2022 | 4897-84-1

Computed Properties of 4897-84-1, Methyl 4-bromobutyrate,also as known as 4-Bromobutyric acid methyl ester, is a useful research compound. Its molecular formula is C5H9BrO2 and its molecular weight is 181.03 g/mol. The purity is usually 95%.
4-Bromobutyric acid methyl ester is a synthetic compound that can be used to inhibit the activity of the G1 phase cyclin-dependent kinases. It has been shown to inhibit protein synthesis by alkylating the amino groups of proteins and fatty acids. 4-Bromobutyric acid methyl ester also inhibits the growth of cancer cell lines, such as renal carcinoma cells. The mechanism of action for this drug is not well understood, but it may be due to its ability to bind with monoclonal antibodies and enter kidney cells by passive diffusion., 4897-84-1.

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 4897-84-1, formula is C5H9BrO2, Name is Methyl 4-bromobutanoate. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Computed Properties of 4897-84-1.

Brzeskiewicz, Jakub;Loska, Rafal research published 《 Palladium-Catalyzed Access to Benzocyclobutenone-Derived Ketonitrones via C(sp2)-H Functionalization》, the research content is summarized as follows. The palladium-catalyzed C(sp2)-H functionalization of bromoaryl aldonitrones 2-Br-3-R-4-R1-5-R2-6-R3C6C(R4)(R5)CH=N(R6)(=O) [R = H; R1 = H, F, t-Bu, COOMe; RR1 = -CH=CH-CH=CH-; R2 = H, Cl, CF3, NEt2; R1R2 = -CH2OCH2-; R3 = H, F; R4 = H, Me, 4-nitrophenyl; R5 = Me, Bn, n-Bu; R4R5 = -(CH2)4-, -(CH2)2O(CH2)2-, -CH2CH=CHCH2-; R6 = Me, Bn, PhCH2CH2, (CH2)3COOMe] leading to benzocyclobutenone-derived ketonitrones I is described. This method allows for the preparation of a wide range of strained, four-membered ketonitrones with broad functional group tolerance. Downstream transformations of the formed products were readily demonstrated, illustrating the synthetic utility of the obtained benzocyclobutenone-derived nitrones for the construction of polycyclic nitrogen-containing scaffolds, e.g., II.

Computed Properties of 4897-84-1, Methyl 4-bromobutyrate,also as known as 4-Bromobutyric acid methyl ester, is a useful research compound. Its molecular formula is C5H9BrO2 and its molecular weight is 181.03 g/mol. The purity is usually 95%.
4-Bromobutyric acid methyl ester is a synthetic compound that can be used to inhibit the activity of the G1 phase cyclin-dependent kinases. It has been shown to inhibit protein synthesis by alkylating the amino groups of proteins and fatty acids. 4-Bromobutyric acid methyl ester also inhibits the growth of cancer cell lines, such as renal carcinoma cells. The mechanism of action for this drug is not well understood, but it may be due to its ability to bind with monoclonal antibodies and enter kidney cells by passive diffusion., 4897-84-1.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary